Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799817 | 0.56 | MAOA (0.44) | KDM4ERAB9AMEN1ALDH1A1MAPT | |
| SCHEMBL29638852 | 0.55 | MAOA (0.60) | KDM4ERAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL29503343 | 0.55 | MAOA (0.60) | KDM4ERAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL3628239 | 0.55 | MAOA (0.60) | KDM4ERAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL8546257 | 0.52 | — | — | |
| SCHEMBL29697456 | 0.49 | MAOA (0.46) | PTGS1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5266267 | 0.49 | MAOA (0.46) | PTGS1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12640638 | 0.48 | MAOA (0.44) | ATMMEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL30952752 | 0.48 | MAOA (0.44) | PTGS1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL76778 | 0.47 | ALDH1A1 (0.54) | KDM4ERAB9ANPC1PTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204323-A | Use of tricyclic 1,4-dihydro-1,4-dioxo-1 H-naphthalene derivatives, resulting novel compounds and therapeutical use thereof | INNOTHERA LAB SA (FR) | 1999-01-06 | — | — | CN | disclosed |