Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846650 | 0.79 | LTA4H (0.43) | LTA4HBCHEHSD11B1 | |
| SCHEMBL2607208 | 0.78 | SMN1; SMN2 (0.45) | KDM4ELTA4HSLC6A1SLC6A11ALDH1A1 | |
| SCHEMBL15142809 | 0.78 | SMN1; SMN2 (0.45) | KDM4ELTA4HSLC6A1SLC6A11ALDH1A1 | |
| SCHEMBL15142807 | 0.78 | SMN1; SMN2 (0.45) | KDM4ELTA4HSLC6A1SLC6A11ALDH1A1 | |
| SCHEMBL27564549 | 0.78 | SLC6A1 (0.58) | SLC6A1SLC6A11ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2007871 | 0.77 | SMN1; SMN2 (0.47) | KDM4ESLC6A1SLC6A11ALDH1A1CHRNB2 | |
| SCHEMBL28941581 | 0.76 | CHRM5 (0.48) | KDM4ELTA4H | |
| SCHEMBL2204349 | 0.76 | LTA4H (0.43) | LTA4HSLC6A1SLC6A11BCHE | |
| SCHEMBL28750104 | 0.76 | CHRM5 (0.44) | LTA4H | |
| SCHEMBL27564415 | 0.74 | CHRM5 (0.52) | KDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1374959-A | Piperidine quinolyl propyl derivatives, preparation method and compositions containing same | AVENTIS PHARMA SA (FR) | 2002-10-16 | — | — | CN | disclosed |