Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550497 | 0.84 | GAA (0.67) | GAARAPGEF4HTTMAPTKMT2A | |
| SCHEMBL310696 | 0.83 | GAA (0.73) | GAARAPGEF4HTTMAPTKMT2A | |
| SCHEMBL27551316 | 0.82 | KMT2A (0.47) | GAAHTTMAPTKMT2AHTR6 | |
| SCHEMBL8137089 | 0.82 | GAA (0.52) | GAARAPGEF4HTTMAPTKMT2A | |
| SCHEMBL818508 | 0.82 | HTR6 (0.50) | GAAMAPTKMT2AHTR6LMNA | |
| SCHEMBL12409036 | 0.80 | GAA (0.76) | GAARAPGEF4HTTMAPTKMT2A | |
| SCHEMBL26291500 | 0.78 | HTR6 (0.64) | GAARAPGEF4HTTMAPTKMT2A | |
| SCHEMBL7138688 | 0.77 | HTR6 (0.70) | GAARAPGEF4MAPTKMT2AHTR6 | |
| SCHEMBL28422858 | 0.74 | HTR6 (0.73) | GAAKMT2AHTR6LMNAMPO | |
| SCHEMBL12550502 | 0.74 | LMNA (0.56) | GAAHTTMAPTKMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1258292-A | Olefin polymerization catalysts contg. group 8-10 transition metals, bidentate ligands, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEM CO (US) | 2000-06-28 | — | — | CN | disclosed |