SCHEMBL275672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2889646	0.86	TSHR (0.57)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL742381	0.84	ALDH1A1 (0.55)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL692577	0.83	KMT2A (0.60)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL6989419	0.83	ALDH1A1 (0.59)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL30955356	0.82	ALDH1A1 (0.51)	KMT2AALDH1A1MAPTGAAKDM4E
	SCHEMBL2459917	0.82	ALDH1A1 (0.51)	KMT2AALDH1A1MAPTGAAKDM4E
	SCHEMBL29221076	0.82	ATM (0.51)	LMNAKMT2AALDH1A1MAPTGAA
	SCHEMBL6284647	0.82	LMNA (0.58)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL27872409	0.81	MAPT (0.44)	LMNAKMT2AALDH1A1MAPTPKM
	SCHEMBL7010910	0.80	ALDH1A1 (0.46)	LMNAKMT2AALDH1A1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.