Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824523 | 0.82 | CYP1A2 (0.70) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13070648 | 0.81 | CYP1A2 (0.44) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14985677 | 0.76 | CSNK1G1 (0.77) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2707978 | 0.75 | HPGD (0.37) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL4192180 | 0.74 | CES1 (0.62) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL30398896 | 0.74 | CES1 (0.62) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18831115 | 0.72 | CSNK1G1 (0.51) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL16946150 | 0.70 | MAP3K11 (0.38) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2507584 | 0.70 | MAPT (0.70) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13534020 | 0.69 | CSNK1G1 (0.49) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088368-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ALDH1A1 3957/4885CYP1A2 3826/4885MAPT 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.