Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.36 |
| ▸ | CDC7 | O00311 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756587 | 0.81 | PSEN1 (0.39) | CDK2GSK3BMAP4K4CLK4CDC7 | |
| SCHEMBL2707211 | 0.81 | PSEN1 (0.41) | CYP1A2SMN1; SMN2EGFRERBB2IGF1R | |
| SCHEMBL2705692 | 0.79 | CSNK1G1 (0.49) | HPGDGFERHSD17B10CDK2GSK3B | |
| SCHEMBL22961903 | 0.75 | HPGD (0.44) | HPGDGFERHSD17B10SMN1; SMN2EGFR | |
| SCHEMBL8714236 | 0.75 | CES1 (0.55) | HPGDGFERHSD17B10EGFRERBB2 | |
| SCHEMBL2756789 | 0.75 | ALDH1A1 (0.54) | HPGDHSD17B10CDK2GSK3BMAP4K4 | |
| SCHEMBL18801441 | 0.73 | MAP3K11 (0.36) | SMN1; SMN2ALDH1A1MAPTLMNAFGFR1 | |
| SCHEMBL2756590 | 0.72 | CSNK1G1 (0.61) | HPGDGFERHSD17B10CDK2GSK3B | |
| SCHEMBL9980151 | 0.72 | CSNK1G1 (0.61) | HPGDGFERHSD17B10CDK2GSK3B | |
| SCHEMBL12120558 | 0.72 | HPGD (0.42) | HPGDGFERHSD17B10EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088368-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | HPGD 3745/4885GFER 4808/4885HSD17B10 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.