Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137763 | 0.87 | TET2 (0.39) | TET2ALDH1A1TSHR | |
| SCHEMBL23950 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL3183770 | 0.81 | TET2 (0.38) | TET2ALDH1A1 | |
| Propane SCHEMBL8856062 | 0.79 | TET2 (0.39) | TET2ALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL7560025 | 0.79 | TDP1 (0.36) | TET2ALDH1A1TSHR | |
| Pivalate SCHEMBL30235549 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| Butadiene SCHEMBL16538076 | 0.77 | TET2 (0.33) | TET2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL27075743 | 0.76 | TDP1 (0.38) | TET2ALDH1A1TSHR | |
| SCHEMBL3102112 | 0.76 | — | — | |
| SCHEMBL203037 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100439340-C | 3-cyanoquinolines, 3-cyano-1, 6-naphthyridines, and 3-cyano-1, 7-naphthyridines as protein kinase inhibitors | WYETH CORP (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1419545-A | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | WYETH CORP (US) | 2003-05-21 | — | — | CN | disclosed |