Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KDM5C | P41229 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL285597 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL28789402 | 0.93 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL7784488 | 0.93 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Adipic Acid SCHEMBL28221050 | 0.87 | LMNA (0.69) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| Succinic Acid SCHEMBL140348 | 0.84 | — | — | |
| Succinic Acid SCHEMBL9189068 | 0.84 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL140347 | 0.84 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL9189067 | 0.84 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL14834482 | 0.84 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1APEX1 | |
| Succinic Acid SCHEMBL5738709 | 0.84 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209626-B | 3- hydracrylic acid is produced by recombination yeast | 诺维信股份有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107109347-A | Recombinant host cell for producing 3 hydracrylic acids | 诺维信公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-1414832-A | Enhanced herbicides | APPLIED CARBONCHEMICALS INC (US) | 2003-04-30 | — | — | CN | disclosed |