Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32662599 | 0.92 | CYP1A2 (0.46) | PTGDR2CYP1A2KMT2AALDH1A1TDP1 | |
| SCHEMBL5147272 | 0.87 | CYP1A2 (0.42) | PTGDR2CYP1A2KMT2AALDH1A1TDP1 | |
| SCHEMBL20299855 | 0.87 | BCL9 (0.44) | PTGDR2CYP1A2KMT2AALDH1A1TDP1 | |
| SCHEMBL9226726 | 0.86 | TSHR (0.47) | TSHRPTGDR2CYP1A2KMT2AALDH1A1 | |
| SCHEMBL9226722 | 0.86 | TSHR (0.47) | TSHRPTGDR2CYP1A2KMT2AALDH1A1 | |
| SCHEMBL28102381 | 0.85 | ALDH1A1 (0.46) | PTGDR2CYP1A2KMT2AALDH1A1TDP1 | |
| SCHEMBL5742091 | 0.85 | KMT2A (0.45) | CYP1A2KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL11613240 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1HPGDTAAR1 | |
| Bicarbonate SCHEMBL9219743 | 0.85 | TSHR (0.46) | TSHRPTGDR2CYP1A2KMT2AALDH1A1 | |
| SCHEMBL5742094 | 0.85 | KMT2A (0.45) | CYP1A2KMT2AALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1311787-A | oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA CO LTD (SE) | 2001-09-05 | — | — | CN | disclosed |