Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32662599 | 0.91 | CYP1A2 (0.46) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL2995973 | 0.88 | CYP1A2 (0.44) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL2995979 | 0.88 | CYP1A2 (0.44) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL27573003 | 0.87 | TSHR (0.46) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL20299855 | 0.86 | BCL9 (0.44) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL9226726 | 0.84 | TSHR (0.47) | CYP1A2PTGDR2ALDH1A1MAPTTAAR1 | |
| SCHEMBL9226722 | 0.84 | TSHR (0.47) | CYP1A2PTGDR2ALDH1A1MAPTTAAR1 | |
| SCHEMBL28102381 | 0.84 | ALDH1A1 (0.46) | CYP1A2PTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL5742091 | 0.83 | KMT2A (0.45) | CYP1A2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11613240 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HPGDTAAR1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569895-A4 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1569895-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052844-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | disclosed |