Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 8/20 | 0.74 |
| ▸ | NT5E | P21589 | 1/20 | 0.67 |
| ▸ | PNP | P00491 | 1/20 | 0.65 |
| ▸ | KRAS | P01116 | 5/20 | 0.64 |
| ▸ | GSK3A | P49840 | 2/20 | 0.63 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.63 |
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674769 | 0.91 | HINT1 (0.72) | HINT1NT5EPNPKRASGSK3A | |
| SCHEMBL2675383 | 0.91 | HINT1 (0.72) | HINT1NT5EPNPKRASGSK3A | |
| SCHEMBL10001265 | 0.91 | HINT1 (0.72) | HINT1NT5EPNPKRASGSK3A | |
| SCHEMBL2675390 | 0.90 | HINT1 (0.71) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL14178410 | 0.88 | HINT1 (0.75) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL116165 | 0.88 | HINT1 (0.75) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL15338533 | 0.88 | HINT1 (0.75) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL11965261 | 0.88 | HINT1 (0.75) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL383785 | 0.88 | HINT1 (0.75) | HINT1NT5EPNPKRASGSK3A | |
| 2'-Beta-Methyl-Guanosine SCHEMBL5972612 | 0.87 | HINT1 (0.73) | HINT1NT5EPNPKRASGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100488512-C | Compositions for treatment of cell proliferative disorders and its uses | MARINE POLYMERS TECHNOLOGIES I (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-1335749-A | Method and compositions for treatment of cell proliferative disorders | MARINE POLYMERS TECHNOLOGIES I (US) | 2002-02-13 | — | — | CN | disclosed |