Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 9/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491966 | 0.83 | MAPKAPK2 (0.47) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL26640996 | 0.81 | MAPKAPK2 (0.45) | MAPKAPK2CYP17A1ATRRORCMAP4K4 | |
| SCHEMBL27576193 | 0.77 | MAPKAPK2 (0.40) | MAPKAPK2ATRRORCHDAC4HDAC1 | |
| SCHEMBL1010435 | 0.77 | ATR (0.46) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL6497617 | 0.77 | MAPKAPK2 (0.41) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL31221957 | 0.74 | MAPKAPK2 (0.40) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL18805715 | 0.74 | RORC (0.53) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL18839612 | 0.74 | MAPKAPK2 (0.41) | MAPKAPK2CYP17A1ATRSTK17BSTK17A | |
| SCHEMBL27576229 | 0.73 | LMNA (0.39) | MAPKAPK2CYP17A1ATRRORC | |
| Ethoxycarbonyl Group SCHEMBL27576231 | 0.73 | NAMPT (0.40) | MAPKAPK2CYP17A1ATRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335847-A | Sulfonamide compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-02-13 | — | — | CN | disclosed |