Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576348 | 0.90 | HRH3 (0.41) | TSHRFFAR4FFAR1EPHX1 | |
| SCHEMBL5113740 | 0.84 | TSHR (0.44) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5104269 | 0.81 | PPARG (0.45) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5100773 | 0.75 | PPARG (0.41) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5101275 | 0.73 | LMNA (0.41) | TSHRLMNAMAPTRXFP1FFAR1 | |
| SCHEMBL14265709 | 0.72 | MAPT (0.43) | TSHRLMNAMAPTRXFP1KMT2A | |
| SCHEMBL5113340 | 0.71 | PPARG (0.49) | TSHRLMNAMAPTRXFP1CYSLTR2 | |
| SCHEMBL5113265 | 0.71 | TSHR (0.42) | TSHRLMNAMAPTRXFP1ESR1 | |
| SCHEMBL5107694 | 0.71 | KMT2A (0.42) | TSHRLMNAMAPTRXFP1CYSLTR2 | |
| SCHEMBL5113624 | 0.71 | KMT2A (0.42) | TSHRLMNAMAPTRXFP1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | claimed |
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | disclosed |