Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113265 | 0.84 | TSHR (0.42) | TSHRLMNAMAPTRXFP1CYSLTR2 | |
| SCHEMBL27576342 | 0.84 | TSHR (0.43) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5104269 | 0.82 | PPARG (0.45) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5114276 | 0.82 | MAPT (0.47) | LMNAMAPTRXFP1FFAR4PPARG | |
| SCHEMBL5100773 | 0.82 | PPARG (0.41) | TSHRLMNAMAPTRXFP1FFAR4 | |
| SCHEMBL5101275 | 0.81 | LMNA (0.41) | TSHRLMNAMAPTRXFP1CYSLTR2 | |
| SCHEMBL27576348 | 0.81 | HRH3 (0.41) | TSHRFFAR4PPARGLTA4HFFAR1 | |
| SCHEMBL5113340 | 0.78 | PPARG (0.49) | TSHRLMNAMAPTRXFP1CYSLTR2 | |
| SCHEMBL5107151 | 0.76 | PPARG (0.57) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5101223 | 0.76 | TSHR (0.39) | TSHRLMNAMAPTRXFP1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | claimed |
| US-7348426-B1 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | DR. REDDY'S LABORATIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | disclosed |