Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576386 | 0.93 | METAP2 (0.38) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27538282 | 0.93 | METAP2 (0.38) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27538336 | 0.93 | METAP2 (0.38) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27562663 | 0.92 | METAP2 (0.37) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27562664 | 0.92 | METAP2 (0.37) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27541778 | 0.91 | METAP2 (0.35) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL27560038 | 0.87 | KMT2A (0.37) | METAP2CTSSCTSKALDH1A1RECQL | |
| SCHEMBL27538585 | 0.86 | METAP2 (0.34) | METAP2CTSSCTSKCASRTSHR | |
| SCHEMBL6897605 | 0.84 | LTA4H (0.41) | METAP2CASRPPARAPPARGGMNN | |
| SCHEMBL27570950 | 0.84 | METAP2 (0.35) | METAP2CTSSCTSKCASRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |