Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 9/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.51 |
| ▸ | ITGAL | P20701 | 1/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927953 | 1.00 | CTSL (0.54) | CTSLCYP3A4CYP2C19TACR1ITGB2 | |
| SCHEMBL2342532 | 0.90 | SSTR3 (0.52) | ITGB2ICAM1ITGALSSTR3SSTR1 | |
| SCHEMBL1928434 | 0.88 | SSTR3 (0.46) | CTSLTACR1ITGB2ICAM1ITGAL | |
| SCHEMBL4244384 | 0.86 | KMT2A (0.59) | SSTR3SSTR1MEN1KMT2A | |
| SCHEMBL1927088 | 0.86 | FPR2 (0.56) | ITGB2ICAM1ITGALSSTR3SSTR1 | |
| SCHEMBL27564526 | 0.86 | FPR2 (0.56) | ITGB2ICAM1ITGALSSTR3SSTR1 | |
| SCHEMBL13579138 | 0.85 | SSTR3 (0.49) | TACR1ITGB2ICAM1ITGALSSTR3 | |
| SCHEMBL4247165 | 0.85 | KMT2A (0.54) | SSTR3SSTR1KMT2A | |
| SCHEMBL1723433 | 0.84 | SSTR3 (0.47) | ITGB2ICAM1ITGALSSTR3SSTR1 | |
| SCHEMBL14341130 | 0.84 | SSTR3 (0.48) | TACR1ITGB2ICAM1ITGALSSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1391474-A | 5-membered heterocyclic derivatives, their preparation and their use as medicaments | SOD CONSEILS RECH APPLIC (FR) | 2003-01-15 | — | — | CN | claimed |