Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896134 | 0.82 | ALDH1A1 (0.51) | ALDH1A1ABCB1CCR6PAX8KMT2A | |
| SCHEMBL28660255 | 0.75 | KMT2A (0.54) | ALDH1A1CCR6PAX8KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL8721704 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CCR6PAX8KMT2ASIGMAR1 | |
| SCHEMBL16665613 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CCR6PAX8KMT2AMAPK1 | |
| SCHEMBL15479668 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CCR6PAX8KMT2AMAPK1 | |
| SCHEMBL12220545 | 0.74 | SYK (0.69) | SYKALDH1A1CTRB1KMT2ARAB9A | |
| SCHEMBL20147823 | 0.74 | ALDH1A1 (0.53) | ALDH1A1ABCB1CCR6PAX8KMT2A | |
| SCHEMBL9752422 | 0.74 | ALDH1A1 (0.53) | ALDH1A1ABCB1CCR6PAX8KMT2A | |
| SCHEMBL10107202 | 0.73 | ALDH1A1 (0.56) | ALDH1A1ABCB1CCR6PAX8KMT2A | |
| SCHEMBL23836500 | 0.73 | ABCB1 (0.45) | ALDH1A1ABCB1CCR6PAX8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1432020-A | Purine derivatives | PFIZER LTD (US) | 2003-07-23 | — | — | CN | disclosed |