Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.69 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528148 | 0.92 | SYK (0.64) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL8900969 | 0.92 | CTRB1 (0.74) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL213314 | 0.92 | SYK (0.64) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL2636259 | 0.92 | SYK (0.64) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL14595243 | 0.92 | CTRB1 (0.74) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL27351869 | 0.91 | SYK (0.63) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL15288192 | 0.91 | SYK (0.63) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL10250740 | 0.91 | SYK (0.63) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL20315241 | 0.91 | CTRB1 (0.76) | SYKCTRB1ATMCTSKCTSL | |
| SCHEMBL1051345 | 0.90 | SYK (0.62) | SYKCTRB1ATMCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661621-B2 | Self-immolative probes for enzyme activity detection | ENZO LIFE SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230159563-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11572398-B2 | GLP-1 derivatives and uses thereof | NOVO NORDISK A/S (DK) | 2023-02-07 | — | — | US | disclosed |
| US-20200291448-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | ENZO LIFE SCIENCES, INC. (US) | 2020-09-17 | — | — | US | disclosed |
| CN-110016020-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109384778-A | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 铁木医药有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-109369635-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-108912111-A | compounds and pharmaceutical compositions | 铁木医药有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105408328-B | sGC stimulators | 铁木医药有限公司 | 2018-11-16 | — | — | CN | disclosed |
| US-20170320927-A1 | GLP-1 Derivatives and Uses Thereof | NOVO NORDISK A/S (DK) | 2017-11-09 | — | — | US | disclosed |
| US-9574222-B2 | Self-immolative probes for enzyme activity detection | ENZO LIFE SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-1613420-B1 | METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS | INSTRACTION GMBH (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | SPR, ABCG2, SHBG | SYK 2408/4885CTRB1 1252/4885ATM 4670/4885 |
| US-11572398-B2 | GLP-1 derivatives and uses thereof | GLP1R, GIPR, GCG | SYK 4428/4885CTRB1 1130/4885ATM 4864/4885 |
| US-11661621-B2 | Self-immolative probes for enzyme activity detection | MGAM, SI, ENGASE | SYK 712/4885CTRB1 2669/4885ATM 1887/4885 |
| US-20200291448-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | MGAM, SI, ENGASE | SYK 712/4885CTRB1 2669/4885ATM 1887/4885 |
| US-20170320927-A1 | GLP-1 Derivatives and Uses Thereof | GLP1R, GIPR, GCG | SYK 4428/4885CTRB1 1130/4885ATM 4864/4885 |
| US-20230159563-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | KRAS, NRAS, HRAS | SYK 3852/4885CTRB1 1304/4885ATM 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.