Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712159 | 0.93 | SMN1; SMN2 (0.66) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL1197247 | 0.93 | MAPT (0.78) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL9051375 | 0.85 | FFAR1 (0.64) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL25342051 | 0.85 | HDAC3 (0.76) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL711512 | 0.85 | MAPT (0.66) | MAPTRXFP1HDAC11FFAR1 | |
| SCHEMBL25173309 | 0.85 | MAPT (0.66) | MAPTRXFP1HDAC11FFAR1 | |
| SCHEMBL10095169 | 0.85 | MAPT (0.66) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL25170050 | 0.85 | MAPT (0.66) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL12329336 | 0.85 | MAPT (0.66) | MAPTRXFP1HDAC6HDAC3MAPK1 | |
| SCHEMBL8987510 | 0.85 | MAPT (0.71) | MAPTRXFP1HDAC6HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101070316-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARMA GMBH (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1331862-C | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (DE) | 2007-08-15 | — | — | CN | disclosed |