Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | PTPRB | P23467 | 1/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | PTEN | P60484 | 1/20 | 0.59 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70271 | 0.92 | KEAP1 (0.74) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL10982620 | 0.90 | KEAP1 (0.71) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL27712159 | 0.89 | SMN1; SMN2 (0.66) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL8435278 | 0.86 | FFAR1 (0.80) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL27578485 | 0.85 | MAPT (0.68) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL4407150 | 0.84 | KEAP1 (0.63) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL30638471 | 0.84 | KEAP1 (0.63) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL12646398 | 0.83 | FFAR1 (0.69) | FFAR1KEAP1FFAR4 | |
| SCHEMBL19501287 | 0.82 | ALDH1A1 (0.62) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL8614478 | 0.82 | KEAP1 (0.67) | FFAR1KEAP1PTPRBCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |
| EP-0142324-B1 | PHENYLALKANOIC ACID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-04 | — | — | EP | disclosed |
| US-4175202-A | 4,5,6-Trinor-3,7,-inter-m-phenylene prostaglandin A1 analogs | THE UPJOHN COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| US-4084058-A | HYPOTENSIVES, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4053485-A | OPTICALLY ACTIVE OR RACEMIC MIXTURES | THE UPJOHN COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032560-A | OXA PHENYLENE PROSTAGLANDIN ANALOGS | THE UPJOHN COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4020097-A | HYPOTENSIVE, ANTICOAGULANT | THE UPJOHN COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-3997566-A | Tricyclic prostaglandin | THE UPJOHN COMPANY (US) | 1976-12-14 | — | — | US | disclosed |