Oxirane

Oxirane

SCHEMBL27578564

C1CO1.CCCOC1CO1

nearest known ligand 0.34

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4922574 0.93
SCHEMBL13172629 0.93
SCHEMBL13172387 0.93
SCHEMBL28842306 0.89 CHRM2 (0.34) SMN1; SMN2
Morpholine SCHEMBL28471707 0.78 MEN1 (0.39)
SCHEMBL3379348 0.78
SCHEMBL4915956 0.78
SCHEMBL27274099 0.77 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1
SCHEMBL94047 0.76
SCHEMBL1706788 0.74 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104876468-A Functionalized polycarboxylic acid water reducer matched with silica fume and preparation method thereof UNIV WUHAN TECH 2015-09-02 CN claimed
CN-104193215-A Ternary block macromonomer graft copolymerization high-property polycarboxylic acid water-reducing agent and preparation method thereof UNIV WUHAN TECH 2014-12-10 CN claimed
CN-100526409-C Slurry composition and CMP method using the same SAMSUNG ELECTRONICS CO LTD (KR) 2009-08-12 CN claimed
CN-1637102-A Slurry composition and CMP method using the same SAMSUNG ELECTRONICS CO LTD (KR) 2005-07-13 CN claimed
CN-105229110-A Chemical mechanical polishing composition selective for oxides and nitrides with high removal rate and low defectivity CABOT MICROELECTRONICS CORP 2016-01-06 CN disclosed
CN-104876468-A Functionalized polycarboxylic acid water reducer matched with silica fume and preparation method thereof UNIV WUHAN TECH 2015-09-02 CN disclosed
CN-104860567-A Disperse thickening agent for phosphorus gypsum based self-leveling mortar and preparation method UNIV WUHAN TECH 2015-08-26 CN disclosed
CN-104284960-A CMP compositions selective for oxide and nitride with high removal rate and low defectivity CABOT MICROELECTRONICS CORP 2015-01-14 CN disclosed
CN-104193215-A Ternary block macromonomer graft copolymerization high-property polycarboxylic acid water-reducing agent and preparation method thereof UNIV WUHAN TECH 2014-12-10 CN disclosed
CN-101874061-B Particles obtained from emulsions CSIR 2014-09-17 CN disclosed
CN-102939342-A Formulations suitable for use as anti-graffiti coatings with improved wetting properties EVONIK DEGUSSA GMBH 2013-02-20 CN disclosed
CN-101679835-B Antifouling composition, process for producing the same, and processed article ASAHI GLASS CO LTD 2012-12-26 CN disclosed
CN-102575229-A Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products UNIV JOHNS HOPKINS 2012-07-11 CN disclosed
CN-102030897-A Hydrogenated castor oil block polyether as well as preparation method and application thereof NANJING YANGZIHONG LIYUAN CHEMICALS CO LTD 2011-04-27 CN disclosed
CN-101874061-A Particles obtained from emulsions CSIR (ZA) 2010-10-27 CN disclosed
CN-101815772-A Thermally conductive composition NAT STARCH CHEM INVEST 2010-08-25 CN disclosed
CN-100482754-C Hydrophilic coating of medical implements LIFESCAN INC (US) 2009-04-29 CN disclosed
CN-1914316-A Stabilization of enzymes CSIR (ZA) 2007-02-14 CN disclosed
CN-1454952-A Hydrophilic coating of medical implements LIFE SCANNING INC (US) 2003-11-12 CN disclosed
CN-85106838-A High polymer solid electrolyte composed of cross-linked copolymer 1987-03-11 CN disclosed