SCHEMBL27579727

SCHEMBL27579727

C[C]1Nc2ccc(-c3ccc(F)c(Cl)c3)cc2C(C)(C)O1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 0.74
NR3C1 P04150 1/20 0.74
NR3C2 P08235 1/20 0.74
AR P10275 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870143 0.85 PGR (1.00) PGRNR3C1NR3C2AR
SCHEMBL3874828 0.85 PGR (1.00) PGRNR3C1NR3C2AR
SCHEMBL27579723 0.82 PGR (0.73) PGR
SCHEMBL27579729 0.79 PGR (0.73) PGRNR3C1NR3C2AR
SCHEMBL4907923 0.76 PGR (1.00) PGRNR3C1NR3C2AR
SCHEMBL4907288 0.76 PGR (0.74) PGRNR3C1NR3C2AR
SCHEMBL6770779 0.76 PGR (1.00) PGRNR3C1NR3C2AR
SCHEMBL3524836 0.74 PGR (0.71) PGRNR3C1NR3C2AR
SCHEMBL4162611 0.72 PGR (0.73) PGRNR3C1NR3C2AR
SCHEMBL27470035 0.72 PGR (0.70) PGRNR3C1NR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1349413-A Contraceptive compositions containing quinazolinone and benzoxazine derivatives AMERICAN HOME PROD (US) 2002-05-15 CN disclosed