Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907923 | 0.85 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL3981718 | 0.83 | PGR (1.00) | PGR | |
| SCHEMBL4906094 | 0.81 | PGR (0.81) | PGR | |
| SCHEMBL3874828 | 0.81 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27579727 | 0.76 | PGR (0.74) | PGRNR3C1NR3C2AR | |
| SCHEMBL4914397 | 0.75 | PGR (0.78) | PGRNR3C1NR3C2AR | |
| SCHEMBL3870143 | 0.75 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL4915239 | 0.75 | PGR (0.82) | PGRNR3C1NR3C2AR | |
| SCHEMBL6770779 | 0.74 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27470035 | 0.73 | PGR (0.70) | PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113964-A1 | 7-Aryl 1,5-Dihydro-4,1-Benzoxazepin-2(3H)-One Derivatives and Their Use As Progesterone Receptor Modulators | WYETH (US) | 2008-05-15 | — | — | US | claimed |
| US-20050215539-A1 | 7-aryl 1,5-dihydro-4, 1-benzoxazepin-2(3H)-one derivatives and their use as progesterone receptor modulators | WYETH (US) | 2005-09-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113964-A1 | 7-Aryl 1,5-Dihydro-4,1-Benzoxazepin-2(3H)-One Derivatives and Their Use As Progesterone Receptor Modulators | PGR, GPER1, PGRMC2 | PGR 1/4885NR3C1 40/4885NR3C2 6/4885 |
| US-20050215539-A1 | 7-aryl 1,5-dihydro-4, 1-benzoxazepin-2(3H)-one derivatives and their use as progesterone receptor modulators | PGR, GPER1, PGRMC2 | PGR 1/4885NR3C1 40/4885NR3C2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.