Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074992 | 1.00 | ACE (0.45) | ACEMAPTTDP1POLBITGB3 | |
| SCHEMBL6074471 | 0.84 | L3MBTL1 (0.50) | POLBBCHEACHEKMT2AALDH1A1 | |
| SCHEMBL28138297 | 0.83 | ACE (0.61) | ACETDP1CCKBRCTSLMEN1 | |
| SCHEMBL28138300 | 0.83 | ACE (0.61) | ACETDP1CCKBRCTSLMEN1 | |
| SCHEMBL6074418 | 0.83 | CYP1A2 (0.47) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6075005 | 0.79 | TDP1 (0.41) | TDP1POLBCTSLMEN1KMT2A | |
| SCHEMBL6074380 | 0.79 | POLB (0.61) | POLBCTSLKMT2AALDH1A1KDM4E | |
| SCHEMBL29452999 | 0.76 | ACE (0.55) | ACECCKBRCTSLMEN1KMT2A | |
| SCHEMBL6074926 | 0.75 | RAB9A (0.61) | MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7137853 | 0.75 | MAPT (0.42) | ACEMAPTTDP1POLBITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1455771-A | Cyclic amine phenyl Beta-3 adrenergic receptor agonists | WYETH LTD (US) | 2003-11-12 | — | — | CN | disclosed |