Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049752 | 0.74 | KDM4E (0.39) | HPGDPOLBNR1H4MAPTALDH1A1 | |
| SCHEMBL9965045 | 0.71 | BCHE (0.49) | HPGDPOLBMAPTNOS3NOS1 | |
| SCHEMBL5417813 | 0.71 | HDAC6 (0.52) | HPGDPOLBCNR1CNR2NR1H4 | |
| SCHEMBL7278528 | 0.70 | NOS2 (0.41) | TLR7POLBNOS3NOS1NOS2 | |
| SCHEMBL22779157 | 0.69 | NR1H4 (0.42) | HPGDPOLBCNR1CNR2NR1H4 | |
| SCHEMBL28254674 | 0.68 | MAPT (0.48) | NR1H4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24408958 | 0.67 | LMNA (0.48) | HPGDNR1H4MAPTALDH1A1KDM4E | |
| SCHEMBL23401592 | 0.66 | POLB (0.40) | POLBCNR1CNR2NR1H4NOS3 | |
| SCHEMBL16972553 | 0.66 | HDAC3 (0.40) | POLBCNR1CNR2NR1H4KDM4E | |
| SCHEMBL24409202 | 0.65 | NR1H4 (0.56) | NR1H4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1377354-A | Certain alkylenediamine-substituted pyrazolo [1, 5-a ] -1, 5-pyrimidines and pyrazolo [1, 5-a ] -1, 3, 5-triazines | NEUROGEN CORP (US) | 2002-10-30 | — | — | CN | claimed |