Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250570 | 0.84 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CYP3A4 | |
| SCHEMBL417319 | 0.84 | CHRM2 (0.47) | CHRM2CHRM4CHRM3ALDH1A1KMT2A | |
| SCHEMBL29726716 | 0.84 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CYP3A4 | |
| SCHEMBL30849529 | 0.84 | CHRM2 (0.47) | CHRM2CHRM4CHRM3ALDH1A1KMT2A | |
| SCHEMBL27224503 | 0.82 | CHRM2 (0.39) | CHRM2CHRM4CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL3000349 | 0.80 | CHRM2 (0.43) | CHRM2CHRM4CHRM3 | |
| SCHEMBL30945484 | 0.78 | CHRM2 (0.43) | CHRM2CHRM4CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL15483937 | 0.78 | CHRM2 (0.43) | CHRM2CHRM4CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL29216831 | 0.77 | CHRM2 (0.43) | CHRM2CHRM4CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL9550332 | 0.76 | CHRM2 (0.44) | CHRM2CHRM4CHRM3CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1359373-A | 6- [ [ (aryl and heteroaryl) oxy ] methyl ] -naphthyl-2-carboximidamide derivatives, process for their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2002-07-17 | — | — | CN | disclosed |