SCHEMBL3000349

SCHEMBL3000349

COC(=O)C1CCCC2CCCCC21

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM3 P20309 1/20 0.43
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
POLB P06746 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL417319 0.92 CHRM2 (0.47) CHRM2CHRM4CHRM3SLC6A2TP53
SCHEMBL30849529 0.92 CHRM2 (0.47) CHRM2CHRM4CHRM3SLC6A2TP53
SCHEMBL31010892 0.84 CHRM2 (0.47) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL29726716 0.84 CHRM2 (0.47) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL19250570 0.84 CHRM2 (0.47) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL5593742 0.83 TP53 (0.33) TP53
SCHEMBL237267 0.81 ALDH1A1 (0.36) TP53
SCHEMBL27581302 0.80 CHRM2 (0.41) CHRM2CHRM4CHRM3
SCHEMBL22188917 0.80 CHRNB2 (0.43) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL11514730 0.80 CHRM2 (0.48) CHRM2CHRM4CHRM3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
CN-103402989-B Tetrazole compound and preparation and application thereof ZAFGEN CORP. (US) 2016-04-06 CN disclosed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
CN-103402989-A Tetrazole compounds and methods of making and using same ZAFGEN CORP 2013-11-20 CN disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
CN-1805957-A Azetidine compounds ASTRAZENECA AB (SE) 2006-07-19 CN disclosed
CN-1359373-A 6- [ [ (aryl and heteroaryl) oxy ] methyl ] -naphthyl-2-carboximidamide derivatives, process for their preparation and their use in therapy SANOFI SYNTHELABO (FR) 2002-07-17 CN disclosed
CN-1193012-A Sulfamine-substituted chemical compound, preparing process therefor, and use as medicine and diagnosis agent and medicine containing same HOECHST AG (DE) 1998-09-16 CN disclosed
WO-1993004070-A1 SUBSTITUTED ACRYLAMIDO-PENICILLANIC ACID DERIVATIVES SMITHKLINE BEECHAM, PLC (GB) 1993-03-04 WO disclosed
EP-0421752-A2 Substituted acrylamido-penicillanic acid derivatives Beecham Group p.l.c. (GB) 1991-04-10 EP disclosed