Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717760 | 0.86 | MAPT (0.52) | MAPTL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL23401444 | 0.86 | LMNA (0.55) | KLKB1CTSBMAPTL3MBTL1TDP1 | |
| SCHEMBL16115868 | 0.84 | L3MBTL1 (0.53) | MAPTL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL25235132 | 0.81 | CYP2C9 (0.65) | KLKB1CTSBLMNATSHRQPCT | |
| SCHEMBL17255718 | 0.80 | GAA (0.55) | KLKB1CTSBMAPTL3MBTL1TDP1 | |
| SCHEMBL29120365 | 0.79 | MAPT (0.67) | MAPTL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL600209 | 0.79 | GAA (0.65) | MAPTL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL10140275 | 0.78 | POLB (0.56) | MAPTL3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL6098089 | 0.78 | MAPT (0.50) | MAPTL3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL2288170 | 0.77 | MAPT (0.53) | MAPTL3MBTL1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1492874-A | Macrolide antibiotics | — | 2004-04-28 | — | — | CN | disclosed |