SCHEMBL27583154

SCHEMBL27583154

O=C(O)CCC(=O)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
ALOX15 P16050 1/20 0.50
HPGD P15428 2/20 0.45
HSD17B10 Q99714 1/20 0.45
AKR1C3 P42330 1/20 0.41
NR4A2 P43354 1/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
RECQL P46063 1/20 0.41
TSHR P16473 1/20 0.40
CYP1A2 P05177 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL22217135 0.94 NR4A2 (0.45) ALDH1A1ALOX15HPGDHSD17B10NR4A2
SCHEMBL125859 0.94 NR4A2 (0.45) ALDH1A1ALOX15HPGDHSD17B10NR4A2
SCHEMBL404782 0.94 ALDH1A1 (0.56) ALDH1A1ALOX15HPGDHSD17B10AKR1C3
SCHEMBL27533156 0.90 ALDH1A1 (0.47) ALDH1A1ALOX15HPGDHSD17B10AKR1C3
SCHEMBL5523432 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15HPGDHSD17B10AKR1C3
SCHEMBL27547208 0.86 ALDH1A1 (0.47) ALDH1A1ALOX15HPGDHSD17B10AKR1C3
SCHEMBL29090806 0.86 ALDH1A1 (0.47) ALDH1A1ALOX15HPGDHSD17B10KMT2A
SCHEMBL9468429 0.86 ALDH1A1 (0.50) ALDH1A1ALOX15HPGDAKR1C3KMT2A
Salicylic Acid SCHEMBL27531453 0.85 ALDH1A1 (0.55) ALDH1A1ALOX15HPGDHSD17B10KMT2A
SCHEMBL28630802 0.84 ALDH1A1 (0.49) ALDH1A1ALOX15HPGDHSD17B10AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111635621-A Environment-friendly film material and preparation method and application thereof 金晖兆隆高新科技股份有限公司 2020-09-08 CN claimed
CN-1728995-A Dosage forms comprising a cetp inhibitor and an HMG-CoA reductase inhibitor PFIZER PROD INC (US) 2006-02-01 CN claimed
CN-1615122-A Pharmaceutical formulation comprising bicalutamide ASTRAZENECA UK LTD (GB) 2005-05-11 CN claimed
CN-1545421-A Pharmaceutical composition comprising a low-solubility and/or acid-sensitive drug and a neutralized acidic polymer �Ʒ� 2004-11-10 CN claimed
CN-1402629-A Pharmaceutical compositions providing enhanced drug concentrations PFIZER PROD INC (US) 2003-03-12 CN claimed
CN-111635621-A Environment-friendly film material and preparation method and application thereof 金晖兆隆高新科技股份有限公司 2020-09-08 CN disclosed
CN-105722392-B Compositions of non-nucleoside reverse transcriptase inhibitors 默沙东公司 2019-07-23 CN disclosed
CN-109078015-A The solid dosage of orexin receptor antagonists 默沙东公司 2018-12-25 CN disclosed
CN-105722392-A Compositions of non-nucleoside reverse transcriptase inhibitors 默沙东公司 2016-06-29 CN disclosed
CN-105492000-A Delayed release cysteamine bead formulations, and methods of making and using the same RAPTOR PHARMACEUTICAL INC 2016-04-13 CN disclosed
CN-102695413-A Stable fatty acid formulations MYCELL HOLDINGS LTD 2012-09-26 CN disclosed
CN-101123951-A Pharmaceutical dosage forms comprising a low-solubility drug and a polymer PFIZER PROD INC (US) 2008-02-13 CN disclosed
CN-1728995-A Dosage forms comprising a cetp inhibitor and an HMG-CoA reductase inhibitor PFIZER PROD INC (US) 2006-02-01 CN disclosed
CN-1688291-A Immediate release dosage forms containing solid drug dispersions PFIZER (US) 2005-10-26 CN disclosed
CN-1681479-A Pharmaceutical compositions of semi-ordered drugs and polymers PFIZER PROD INC (US) 2005-10-12 CN disclosed
CN-1625397-A Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor PFIZER PROD INC (US) 2005-06-08 CN disclosed
CN-1615122-A Pharmaceutical formulation comprising bicalutamide ASTRAZENECA UK LTD (GB) 2005-05-11 CN disclosed
CN-1545421-A Pharmaceutical composition comprising a low-solubility and/or acid-sensitive drug and a neutralized acidic polymer �Ʒ� 2004-11-10 CN disclosed
CN-1458840-A Pharmaceutical composition of cholesteryl ester transfer protein inhibitor PFIZER PROD INC (US) 2003-11-26 CN disclosed
CN-1402629-A Pharmaceutical compositions providing enhanced drug concentrations PFIZER PROD INC (US) 2003-03-12 CN disclosed