SCHEMBL29090806

SCHEMBL29090806

COC(=O)CCC(=O)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
ALOX15 P16050 1/20 0.47
KDM4E B2RXH2 3/20 0.46
LMNA P02545 2/20 0.46
KMT2A Q03164 4/20 0.44
HSD17B10 Q99714 3/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 3/20 0.43
ESRRB O95718 1/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 2/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RECQL P46063 1/20 0.42
AKT1 P31749 1/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404782 0.91 ALDH1A1 (0.56) ALDH1A1ALOX15KDM4EKMT2AHSD17B10
Phthalic Acid SCHEMBL28233805 0.89 ALDH1A1 (0.58) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL27547208 0.87 ALDH1A1 (0.47) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL27583154 0.86 ALDH1A1 (0.50) ALDH1A1ALOX15KDM4EKMT2AHSD17B10
SCHEMBL27469326 0.85 KDM4E (0.50) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL5523432 0.84 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EKMT2AHSD17B10
SCHEMBL9468429 0.83 ALDH1A1 (0.50) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL27554071 0.82 ALDH1A1 (0.54) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL27700678 0.82 KDM4E (0.63) ALDH1A1ALOX15KDM4ELMNAKMT2A
SCHEMBL2500707 0.81 ALDH1A1 (0.49) ALDH1A1ALOX15KDM4ELMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117545509-A Oral delivery of oligonucleotides 四纬生物制药股份有限公司 2024-02-09 CN disclosed
CN-116897206-A Oral delivery of PCSK 9-targeting antisense conjugates 四纬生物制药股份有限公司 2023-10-17 CN disclosed