Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121657 | 0.98 | KDM4E (0.50) | KDM4EHTTALDH1A1GAAPIM1 | |
| SCHEMBL30241191 | 0.98 | KDM4E (0.50) | KDM4EHTTALDH1A1GAAPIM1 | |
| SCHEMBL7374228 | 0.82 | CDC25B (0.48) | HTTPRKCZKMT2ATDP1NR4A1 | |
| SCHEMBL2149297 | 0.81 | NR4A1 (0.59) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL30430793 | 0.81 | NR4A1 (0.59) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 | |
| Bromide SCHEMBL7369447 | 0.81 | CDC25B (0.47) | HTTPRKCZKMT2ATDP1NR4A1 | |
| SCHEMBL6627806 | 0.79 | PRKCZ (0.43) | KDM4EHTTALDH1A1PRKCZKMT2A | |
| SCHEMBL5800959 | 0.79 | SIRT3 (0.56) | KDM4EHTTALDH1A1PIM1SIRT3 | |
| SCHEMBL22389411 | 0.79 | PRKCZ (0.43) | KDM4EHTTALDH1A1PRKCZKMT2A | |
| Hydrochloric Acid SCHEMBL4617820 | 0.79 | NR4A1 (0.57) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100575345-C | 2 type Cannabined receptors are had in conjunction with active Pyridione derivatives | SHIONOGI & CO | 2009-12-30 | — | — | CN | disclosed |
| CN-1492856-A | Pyridone derivative having affinity for cannabinoid 2-type receptor | ��Ұ����ҩ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |