Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30684499 | 0.84 | MAP2K1 (0.54) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL1558087 | 0.81 | MAP2K1 (0.55) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL30713632 | 0.80 | MAP2K1 (0.49) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL2511843 | 0.80 | SLC22A6 (0.58) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL6225557 | 0.80 | MAP2K1 (0.54) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL27583267 | 0.78 | LMNA (0.37) | KMT2AITGB2ICAM1ITGALGRM4 | |
| SCHEMBL1558071 | 0.77 | MAP2K1 (0.51) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL30563475 | 0.76 | MAP2K1 (0.54) | MAP2K1ADORA2AKMT2ACAMKK2AXL | |
| SCHEMBL38663434 | 0.76 | MAP2K1 (0.50) | MAP2K1GPR84ADORA2AMTNR1AKMT2A | |
| SCHEMBL27563140 | 0.75 | DYRK1A (0.41) | GPR84CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1404392-A | Antiviral azaindole derivatives | BRISTOL MYERS SQUIBB CO (US) | 2003-03-19 | — | — | CN | disclosed |