SCHEMBL27584798

SCHEMBL27584798

c1cc(C2=NCCC2)ccn1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
CYP1A2 P05177 1/20 0.60
THRB P10828 1/20 0.60
CYP2C19 P33261 1/20 0.60
CHRNB4 P30926 12/20 0.57
CHRNA3 P32297 12/20 0.57
CHRNA7 P36544 2/20 0.44
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
NISCH Q9Y2I1 1/20 0.42
MAPK14 Q16539 1/20 0.39
NOTUM Q6P988 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165812 0.79 CHRNB4 (0.87) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL15665457 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL2045328 0.76 CHRNB4 (0.57) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL27928338 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL4693339 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL24414772 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL3574404 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
Myosmine SCHEMBL5319476 0.75 ALDH1A1 (1.00) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL23892004 0.75 CHRNB4 (0.50) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL24344048 0.73 CHRNA7 (0.68) ALDH1A1CYP1A2THRBCYP2C19CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117255812-A Blocked bisphenol polydiindane oligomers and compositions, methods of manufacture, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2023-12-19 CN disclosed
CN-111712529-B Method and composition for preparing thermosetting poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2023-02-28 CN disclosed
CN-110066392-B Capped poly (arylene ether) copolymers, methods of making the same, and curable and cured compositions prepared therefrom 高新特殊工程塑料全球技术有限公司 2021-10-08 CN disclosed
CN-111712529-A Method and composition for preparing thermosetting poly (arylene ether) copolymer 沙特基础工业全球技术有限公司 2020-09-25 CN disclosed
CN-110066392-A Poly- (arylene ether) copolymer of sealing end, preparation method and curable compositions prepared therefrom and solidification composition filling 沙特基础工业全球技术有限公司 2019-07-30 CN disclosed
CN-101688119-A Flame retarded thermosets MARTINSWERK GMBH 2010-03-31 CN disclosed
CN-100506915-C Composition comprising functionalized poly (arylene ether) and ethylene-alkyl (meth)acrylate copolymer, method for the preparation thereof, and articles prepared therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-100487022-C Capped poly (arylene ether) compositions and methods of making the same GEN ELECTRIC (NL) 2009-05-13 CN disclosed
CN-100441637-C Thermoset composite composition, method, and article GEN ELECTRIC (US) 2008-12-10 CN disclosed
CN-101283047-A Poly(arylene ether) composition, method, and article GEN ELECTRIC (US) 2008-10-08 CN disclosed
CN-101283073-A Flame retardant compositions and methods GEN ELECTRIC (US) 2008-10-08 CN disclosed
CN-101283029-A Polymer composition, method, and article GEN ELECTRIC (US) 2008-10-08 CN disclosed
CN-100363425-C Poly (arylene ether)-containing thermoset composition in powder form, method for preparation thereof, and articles derived therefrom GEN ELECTRIC (US) 2008-01-23 CN disclosed
CN-101107290-A Curable encapsulant composition and method of making same GEN ELECTRIC (US) 2008-01-16 CN disclosed
CN-1890292-A Capped poly(arylene ether) composition and process GEN ELECTRIC (US) 2007-01-03 CN disclosed
CN-1886458-A Composition comprising functionalized poly (arylene ether) and ethylene-alkyl (meth)acrylate copolymer, method for the preparation thereof, and articles prepared therefrom GEN ELECTRIC (US) 2006-12-27 CN disclosed
CN-1753950-A Thermosetting composite compositions, methods and products GEN ELECTRIC (US) 2006-03-29 CN disclosed
CN-1494574-A Poly (arylene ether)-containing thermoset composition in powder form, method for preparation thereof, and articles derived therefrom ͨ�õ�����˾ 2004-05-05 CN disclosed