Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111729 | 0.84 | NCF1 (0.72) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL16814882 | 0.84 | NCF1 (0.77) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL110730 | 0.82 | NCF1 (0.70) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL16814951 | 0.82 | NCF1 (0.70) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL29505669 | 0.79 | NCF1 (0.87) | NCF1KDM4EHTR1AADRA2CBRD4 | |
| SCHEMBL16814952 | 0.79 | NCF1 (0.57) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL111193 | 0.79 | NCF1 (0.57) | NCF1ALDH1A1RAB9ABRD4MEN1 | |
| SCHEMBL110927 | 0.79 | NCF1 (0.87) | NCF1KDM4EHTR1AADRA2CBRD4 | |
| SCHEMBL28753504 | 0.78 | NCF1 (0.55) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL24018758 | 0.77 | MEN1 (0.62) | NCF1KDM4EALDH1A1MC4RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |