Aniline

Aniline

SCHEMBL27586111

C=C(C(=O)O)C(=O)O.Nc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.55
▸ PBRM1 Q86U86 1/20 0.43
▸ TDP1 Q9NUW8 4/20 0.40
▸ CYP3A4 P08684 3/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ TAAR1 Q96RJ0 1/20 0.40
▸ MAPT P10636 3/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ PARP1 P09874 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ PMP22 Q01453 1/20 0.39
▸ CYP1B1 Q16678 1/20 0.38
▸ RAB9A P51151 2/20 0.37
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10702983 0.86 CYP3A4 (0.55) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL8520890 0.84 TSHR (0.69) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL29429766 0.84 TSHR (0.69) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL4894770 0.84 TSHR (0.69) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL28183759 0.83 TSHR (0.52) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL6049858 0.81 TSHR (0.73) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL8413315 0.81 TSHR (0.73) TSHRPBRM1TDP1CYP3A4HSD17B10
Naphthalene SCHEMBL6741173 0.79 ALOX12 (0.44) TSHRTDP1CYP3A4HSD17B10MAPT
Aniline SCHEMBL3475063 0.79 TSHR (0.61) TSHRPBRM1TDP1CYP3A4HSD17B10
Aniline SCHEMBL28972529 0.78 TSHR (0.69) TSHRPBRM1TDP1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101229107-B Creme photoprotectrice a base d'acide gras OREAL 2013-06-19 — — CN claimed
CN-101011332-B Aqueous fluid photoprotective composition based on an ester-terminated poly(ester amide) polymer OREAL 2012-10-10 — — CN claimed
CN-101926740-A Method for the photostabilization of the dibenzoylmethane derivative OREAL 2010-12-29 — — CN claimed
CN-101229107-A Creme photoprotectrice a base d'acide gras OREAL (FR) 2008-07-30 — — CN claimed
CN-101219093-A Cosmetic composition containing a dibenzoylmethane derivative and a siloxanic benzoate arylalkyl amide derivative OREAL (FR) 2008-07-16 — — CN claimed
CN-101129302-A Cosmetic use of concave or annular particles of silicone material as an agent making it possible to increase the sun protection factor, aqueous sun-protection composition containing them OREAL (FR) 2008-02-27 — — CN claimed
CN-101011332-A Aqueous fluid photoprotective composition based on an ester-terminated poly(ester amide) polymer OREAL (FR) 2007-08-08 — — CN claimed
CN-1394592-A Solubilizing action of N-acyl amino acid ester para-1,3,5-triazine derivative OREAL (FR) 2003-02-05 — — CN claimed
CN-101683311-B Dithiacyclopentane compound is used for the purposes of skin photoprotection; Novel dithiacyclopentane compound; Containing their compositions L'OREAL (FR) 2016-04-20 — — CN disclosed
CN-103370042-B Based on high water absorbency polymer and methacrylic acid and acrylic acid C 1-C 4the sun-proof fluid composition of aqueous of the cross-linked copolymer of Arrcostab L'OREAL (FR) 2015-12-09 — — CN disclosed
CN-105101946-A Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one specific amide compound OREAL 2015-11-25 — — CN disclosed
CN-102762186-B Composition comprising superabsorbent polymer and gemini surfactant OREAL 2015-06-17 — — CN disclosed
CN-103874479-A Anhydrous sunscreen cream comprising a non-emulsifying elastomeric organopolysiloxane, a matting agent and a non-silicone organic oil thickener OREAL 2014-06-18 — — CN disclosed
CN-103370042-A Fluid aqueous antisun composition based on a superabsorbent polymer and a crosslinked copolymer of methacrylic acid and of a c1-c4 alkyl acrylate OREAL 2013-10-23 — — CN disclosed
CN-101336871-A Sun-protection composition containing the association of a semi-crystalline polymer and hollow latex particles OREAL (FR) 2009-01-07 — — CN disclosed
CN-101229107-A Creme photoprotectrice a base d'acide gras OREAL (FR) 2008-07-30 — — CN disclosed
CN-101219093-A Cosmetic composition containing a dibenzoylmethane derivative and a siloxanic benzoate arylalkyl amide derivative OREAL (FR) 2008-07-16 — — CN disclosed
CN-101129302-A Cosmetic use of concave or annular particles of silicone material as an agent making it possible to increase the sun protection factor, aqueous sun-protection composition containing them OREAL (FR) 2008-02-27 — — CN disclosed
CN-101011332-A Aqueous fluid photoprotective composition based on an ester-terminated poly(ester amide) polymer OREAL (FR) 2007-08-08 — — CN disclosed
CN-1394592-A Solubilizing action of N-acyl amino acid ester para-1,3,5-triazine derivative OREAL (FR) 2003-02-05 — — CN disclosed
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