Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.70 |
| ▸ | PPARG | P37231 | 4/20 | 0.64 |
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSK | P43235 | 6/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782214 | 1.00 | PPARA (0.70) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL2782216 | 1.00 | PPARA (0.70) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL5369011 | 0.93 | PPARA (0.67) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL2781907 | 0.90 | PPARA (0.58) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL2781905 | 0.90 | PPARA (0.58) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL20899650 | 0.90 | PPARA (0.82) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL18555201 | 0.88 | PPARA (0.78) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL18555200 | 0.88 | PPARA (0.78) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL1132901 | 0.87 | PPARA (0.90) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL17051 | 0.87 | PPARA (0.90) | PPARAPPARGCTSSCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1533390-A | Pharmaceutical composition comprising triazaspiro [5.5] undecane derivative as active ingredient | СҰҩƷ��ҵ��ʽ���� | 2004-09-29 | — | — | CN | disclosed |