SCHEMBL17051

SCHEMBL17051

CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O

nearest known ligand 0.90

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.90
PPARG P37231 4/20 0.82
CTSS P25774 3/20 0.72
KLK7 P49862 2/20 0.60
KLK5 Q9Y337 2/20 0.60
ACE P12821 1/20 0.58
FOLH1 Q04609 1/20 0.57
PTPN1 P18031 4/20 0.55
CDC25B P30305 4/20 0.55
PTPN2 P17706 3/20 0.55
CDC25A P30304 2/20 0.55
PTPN6 P29350 1/20 0.55
PTPN11 Q06124 1/20 0.55
RAB9A P51151 1/20 0.55
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
CTSK P43235 1/20 0.54
PPARD Q03181 2/20 0.54
MME P08473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132901 1.00 PPARA (0.90) PPARAPPARGCTSSKLK7KLK5
SCHEMBL828674 1.00 PPARA (0.90) PPARAPPARGCTSSKLK7KLK5
SCHEMBL20899650 0.95 PPARA (0.82) PPARAPPARGCTSSKLK7KLK5
SCHEMBL12130757 0.94 PPARA (0.85) PPARAPPARGCTSSKLK7KLK5
SCHEMBL18555201 0.92 PPARA (0.78) PPARAPPARGCTSSKLK7KLK5
SCHEMBL18555200 0.92 PPARA (0.78) PPARAPPARGCTSSKLK7KLK5
SCHEMBL3820032 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL29229102 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL7057256 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL29556874 0.90 PPARA (0.75) PPARAPPARGCTSSKLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528812-B Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-06-03 CN claimed
CN-119528812-A Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-02-28 CN claimed
CN-118119631-A Programmable selective acylation of polyols 南洋理工大学 2024-05-31 CN claimed
CN-111825742-B Polypeptide solid phase synthesis of CTPA as special coupling agent for amino acid ionic liquid 陈铭 2024-01-30 CN claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
CN-113956183-B Boc-Ser (Bzl) -OH and preparation method thereof 成都市科隆化学品有限公司 2023-06-20 CN claimed
CN-115477648-A Carboline derivative, preparation method thereof and application thereof in preparing antitumor drugs 首都医科大学 2022-12-16 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
CN-113956183-A Boc-Ser (Bzl) -OH and preparation method thereof 成都市科隆化学品有限公司 2022-01-21 CN claimed
EP-0357750-B1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES BIORESEARCH INC (US) 1994-07-13 EP claimed
JP-61010598-A None JP disclosed
JP-60161999-A None JP disclosed
JP-63190900-A None JP disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
US-4028315-A Solid phase synthesis of peptides E. R. SQUIBB & SONS, INC. (US) 1977-06-07 US disclosed
US-4000259-A DIABETES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US disclosed
US-3992530-A [D-2-(1,4-Cyclohexadienyl)gly]6 -des-gly10 -lrh nonapeptide amides AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-16 US disclosed
US-3974135-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same FOLKERS KARL 1976-08-10 US disclosed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP PPARA 1878/4885PPARG 853/4885CTSS 2330/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 PPARA 1752/4885PPARG 2783/4885CTSS 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.