SCHEMBL1132901

SCHEMBL1132901

CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O

nearest known ligand 0.90

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.90
PPARG P37231 4/20 0.82
CTSS P25774 3/20 0.72
KLK7 P49862 2/20 0.60
KLK5 Q9Y337 2/20 0.60
ACE P12821 1/20 0.58
FOLH1 Q04609 1/20 0.57
PTPN1 P18031 4/20 0.55
CDC25B P30305 4/20 0.55
PTPN2 P17706 3/20 0.55
CDC25A P30304 2/20 0.55
PTPN6 P29350 1/20 0.55
PTPN11 Q06124 1/20 0.55
RAB9A P51151 1/20 0.55
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
CTSK P43235 1/20 0.54
PPARD Q03181 2/20 0.54
MME P08473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828674 1.00 PPARA (0.90) PPARAPPARGCTSSKLK7KLK5
SCHEMBL17051 1.00 PPARA (0.90) PPARAPPARGCTSSKLK7KLK5
SCHEMBL20899650 0.95 PPARA (0.82) PPARAPPARGCTSSKLK7KLK5
SCHEMBL12130757 0.94 PPARA (0.85) PPARAPPARGCTSSKLK7KLK5
SCHEMBL18555201 0.92 PPARA (0.78) PPARAPPARGCTSSKLK7KLK5
SCHEMBL18555200 0.92 PPARA (0.78) PPARAPPARGCTSSKLK7KLK5
SCHEMBL3820032 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL29229102 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL7057256 0.91 PPARA (0.76) PPARAPPARGCTSSKLK7KLK5
SCHEMBL29556874 0.90 PPARA (0.75) PPARAPPARGCTSSKLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956183-B Boc-Ser (Bzl) -OH and preparation method thereof 成都市科隆化学品有限公司 2023-06-20 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
CN-113956183-A Boc-Ser (Bzl) -OH and preparation method thereof 成都市科隆化学品有限公司 2022-01-21 CN claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
US-20260070896-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2026-03-12 US disclosed
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-02-12 US disclosed
US-12472165-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-11-18 US disclosed
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN THERAPEUTICS LTD (US) 2025-10-30 US disclosed
US-20250320234-A1 LONP1 INHIBITOR COMPOUNDS, USES AND METHODS PRETZEL THERAPEUTICS, INC. (US) 2025-10-16 US disclosed
US-12404266-B2 Heterocycle derivatives for treating TRPM3 mediated disorders KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-09-02 US disclosed
WO-1992000995-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-01-23 WO disclosed
EP-0105193-B1 SPERGUALIN-RELATED COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1988-08-24 EP disclosed
US-4529549-A Compound containing guanidine and amino groups ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-07-16 US disclosed
US-4507232-A Peptide derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 1985-03-26 US disclosed
EP-0105193-A2 Spergualin-related compounds, processes for the preparation thereof and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1984-04-11 EP disclosed
US-4346078-A Novel anticoagulant agmatine derivatives and process for the preparation thereof RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1982-08-24 US disclosed
US-4127540-A Novel derivatives of δ-endorphins, intermediates therefor, and compositions and methods employing said derivatives VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US disclosed
US-4093574-A Somatostatin analogs and intermediates thereto ELI LILLY AND COMPANY (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP PPARA 1878/4885PPARG 853/4885CTSS 2330/4885
US-20250320234-A1 LONP1 INHIBITOR COMPOUNDS, USES AND METHODS LONP1, NLN, ACAT1 PPARA 2100/4885PPARG 1869/4885CTSS 871/4885
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 PPARA 4425/4885PPARG 4266/4885CTSS 1265/4885
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE GFRA3, IL6ST, GFRA1 PPARA 4461/4885PPARG 4310/4885CTSS 1454/4885
US-12472165-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 PPARA 4317/4885PPARG 4202/4885CTSS 653/4885
US-12404266-B2 Heterocycle derivatives for treating TRPM3 mediated disorders TRPM4, TRPM6, TRPM2 PPARA 2642/4885PPARG 1792/4885CTSS 1306/4885
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 PPARA 4317/4885PPARG 4202/4885CTSS 653/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 PPARA 1752/4885PPARG 2783/4885CTSS 3839/4885
US-20260070896-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS TRPM6, TRPV3, TRPM2 PPARA 1531/4885PPARG 981/4885CTSS 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.