Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166296 | 1.00 | HDAC4 (0.46) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL21571117 | 1.00 | HDAC4 (0.46) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL267944 | 0.96 | CTSK (0.46) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL21994806 | 0.95 | CTSK (0.47) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL21994809 | 0.95 | CTSK (0.47) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL21409067 | 0.91 | CTSK (0.44) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL21409064 | 0.91 | CTSK (0.44) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL20179503 | 0.89 | ITGB3 (0.48) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL28937294 | 0.89 | ITGB3 (0.48) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL31407357 | 0.88 | CTSK (0.43) | HDAC4HDAC1HDAC6ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1538951-B | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | DOMPE SPA | 2013-08-28 | — | — | CN | disclosed |
| CN-1538951-A | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | ��ķ�ɷ�����˾ | 2004-10-20 | — | — | CN | disclosed |