Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616224 | 0.89 | KMT2A (0.46) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL28204506 | 0.81 | ALDH1A1 (0.50) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL1222681 | 0.79 | KMT2A (0.49) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL2450503 | 0.77 | KMT2A (0.57) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL28781903 | 0.77 | ALDH1A1 (0.59) | KMT2AMAPK1ALDH1A1L3MBTL1PAM | |
| SCHEMBL27623792 | 0.77 | ALDH1A1 (0.46) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL21590286 | 0.77 | NPC1 (0.48) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL27620056 | 0.74 | CYP2D6 (0.47) | KMT2AMAPK1ALDH1A1L3MBTL1PAM | |
| SCHEMBL9340889 | 0.74 | MAPK1 (0.50) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL28756463 | 0.73 | TSHR (0.44) | KMT2AMAPK1HPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1420881-A | Beta-amino acid derivs. as inhibitors of matrix metalloproteases and TNF-alpha | BRISTOL MYERS SQUIBB PHARMACEU (US) | 2003-05-28 | — | — | CN | disclosed |