SCHEMBL9340889

SCHEMBL9340889

O=C(Cc1ccccc1)ON1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PAM P19021 1/20 0.49
TSHR P16473 1/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 2/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
AKR1B1 P15121 1/20 0.45
GSK3A P49840 2/20 0.44
GSK3B P49841 2/20 0.44
MGLL Q99685 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
XBP1 P17861 1/20 0.41
HTT P42858 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450503 0.82 KMT2A (0.57) MAPK1ALDH1A1L3MBTL1PAMTSHR
SCHEMBL29139337 0.79 PIK3CA (0.42) HDAC8
SCHEMBL11062218 0.77 ALDH1A1 (0.58) MAPK1ALDH1A1L3MBTL1PAMTSHR
SCHEMBL4041285 0.76 ALDH1A1 (0.49) MAPK1ALDH1A1L3MBTL1KMT2AGSK3A
SCHEMBL269178 0.74 ALDH1A1 (0.41) MAPK1ALDH1A1HPGDGSK3AGSK3B
SCHEMBL2581743 0.74 ALDH1A1 (0.41) MAPK1ALDH1A1TSHRKMT2AHPGD
SCHEMBL27586366 0.74 KMT2A (0.49) MAPK1ALDH1A1L3MBTL1PAMTSHR
SCHEMBL4738882 0.73 LMNA (0.51) MAPK1ALDH1A1TSHRKMT2AHPGD
SCHEMBL25916425 0.73 KMT2A (0.49) MAPK1ALDH1A1L3MBTL1PAMTSHR
SCHEMBL31121818 0.73 ALDH1A1 (0.37) ALDH1A1HPGDGSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106922129-B Methods of conjugating polypeptides 免疫医疗有限责任公司 2024-02-20 CN disclosed
EP-0363211-B1 1Alpha or 24R,25-Dihydroxy vitamin D3 derivatives, process for their production and assay method using the same ASAHI CHEMICAL IND (JP) 1994-07-06 EP disclosed
US-5214170-A Radioimmunoassay TOYO JOZO KABUSHIKI KAISHA (JP) 1993-05-25 US disclosed
US-5202266-A 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-04-13 US disclosed
EP-0312360-B1 25-HYDROXY VITAMIN D3 DERIVATIVES TOYO JOZO KABUSHIKI KAISHA (JP) 1992-06-17 EP disclosed
US-5117018-A 1α (or 24R), 25-dihydroxy vitamin D3 derivatives TOYO JOZO KABUSHIKI KAISHA (JP) 1992-05-26 US disclosed
US-5075465-A 25-HYDROXY VITAMIN D3 DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND ASSAY METHOD USING THE SAME TOYO JOZO KABUSHIKI KAISHA (JP) 1991-12-24 US disclosed
EP-0363211-A1 1Alpha or 24R,25-Dihydroxy vitamin D3 derivatives, process for their production and assay method using the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-04-11 EP disclosed
EP-0312360-A2 25-Hydroxy vitamin D3 derivatives TOYO JOZO KABUSHIKI KAISHA (JP) 1989-04-19 EP disclosed
US-4495151-A Element for immunoassay TOYO JOZO KABUSHIKI KAISHA (JP) 1985-01-22 US disclosed