Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.58 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.58 |
| ▸ | BTK | Q06187 | 13/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.50 |
| ▸ | LCK | P06239 | 5/20 | 0.50 |
| ▸ | SRC | P12931 | 5/20 | 0.50 |
| ▸ | JAK3 | P52333 | 4/20 | 0.50 |
| ▸ | ITK | Q08881 | 4/20 | 0.50 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | HCK | P08631 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176242 | 0.81 | NUDT14 (0.58) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL1614407 | 0.81 | SRC (0.49) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL27604369 | 0.80 | ABL1 (0.57) | EGFRLCKSRCABL1HCK | |
| SCHEMBL25069027 | 0.80 | SRC (0.76) | NUDT14NUDT5EGFRLCKSRC | |
| SCHEMBL22364026 | 0.80 | FYN (0.55) | EGFRSRCABL1HCKPIK3CD | |
| SCHEMBL23223317 | 0.79 | NUDT14 (0.50) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL16078942 | 0.79 | BTK (0.53) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL17723004 | 0.77 | SRC (0.52) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL28747962 | 0.76 | NUDT14 (0.61) | NUDT14NUDT5BTKEGFRLCK | |
| SCHEMBL27604421 | 0.76 | RET (0.40) | EGFRLCKSRCJAK3ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |