SCHEMBL27587100

SCHEMBL27587100

c1cc(-c2cccc3cc4ccccc4cc23)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.50
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 4/20 0.48
HPGD P15428 4/20 0.48
HIF1A Q16665 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
CASP1 P29466 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP1B1 Q16678 1/20 0.43
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
MPI P34949 1/20 0.42
KMT2A Q03164 1/20 0.42
TP53 P04637 1/20 0.41
CASP7 P55210 1/20 0.41
CYP1A2 P05177 2/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27655623 0.89 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL12520786 0.86 CYP11B1 (0.58) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL28376300 0.84 ALDH1A1 (0.55) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL27675918 0.84 TNF (0.47) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL4037430 0.84 ALDH1A1 (0.54) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL30340805 0.82 CYP11B1 (0.55) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL29006475 0.82 CYP11B1 (0.55) CYP11B1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL60347 0.82 TNF (0.50) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL30332794 0.82 TNF (0.50) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL1527420 0.81 ALDH1A1 (0.59) ALDH1A1HSD17B10HPGDHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101381276-A Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2009-03-11 CN disclosed
CN-100445245-C Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2008-12-24 CN disclosed
CN-1394195-A Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2003-01-29 CN disclosed