Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606438 | 0.83 | HRH3 (0.38) | TAAR1 | |
| SCHEMBL27606451 | 0.83 | LTA4H (0.44) | LTA4HTAAR1IDO1AGXTALDH1A1 | |
| SCHEMBL27588576 | 0.82 | TAAR1 (0.49) | TAAR1MAOBIDO1AGXT | |
| SCHEMBL27606453 | 0.81 | LTA4H (0.46) | LTA4HTAAR1MAOBIDO1AGXT | |
| SCHEMBL27588547 | 0.80 | CYP3A4 (0.45) | MAOBALDH1A1 | |
| SCHEMBL27322147 | 0.79 | ALDH1A1 (0.45) | LTA4HIDO1ALDH1A1LMNA | |
| SCHEMBL27588562 | 0.79 | ABAT (0.45) | TAAR1IDO1ALDH1A1 | |
| SCHEMBL27606277 | 0.78 | HRH3 (0.40) | TAAR1ALDH1A1SLC6A4 | |
| SCHEMBL27606263 | 0.77 | LTA4H (0.42) | LTA4HMAOBIDO1AGXTALDH1A1 | |
| SCHEMBL28750723 | 0.76 | MAOB (0.41) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |