Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606591 | 0.79 | KEAP1 (0.40) | KEAP1TAAR1 | |
| SCHEMBL27665839 | 0.79 | NOTUM (0.47) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL27606547 | 0.77 | MAPT (0.48) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9162666 | 0.75 | KDM4E (0.46) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9168221 | 0.72 | GAA (0.45) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL27588543 | 0.71 | HRH3 (0.42) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9763550 | 0.64 | MEN1 (0.37) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2096975 | 0.61 | — | — | |
| SCHEMBL3706685 | 0.61 | MAPT (0.45) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6512058 | 0.60 | POLB (0.31) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |