SCHEMBL275907

SCHEMBL275907

c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2cccc3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.40
DHFR P00374 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
WDR5 P61964 1/20 0.37
ALDH1A1 P00352 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP2A6 P11509 1/20 0.37
CYP3A4 P08684 1/20 0.37
TYMP P19971 1/20 0.36
GSK3B P49841 1/20 0.36
ADK P55263 1/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
MEN1 O00255 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368065 1.00 DNMT1 (0.40) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL30616100 1.00 DNMT1 (0.40) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL8595804 0.98 DNMT1 (0.39) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL30436853 0.98 DNMT1 (0.39) DNMT1DHFRGPR84WDR5ALDH1A1
Hydrochloric Acid SCHEMBL8719043 0.97 DNMT1 (0.38) DNMT1DHFRGPR84WDR5ALDH1A1
Hydrochloric Acid SCHEMBL8719044 0.97 DNMT1 (0.38) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL5805612 0.95 GPR84 (0.38) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL8418840 0.94 WDR5 (0.37) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL29124520 0.94 TYMP (0.36) DNMT1DHFRGPR84WDR5ALDH1A1
SCHEMBL8719045 0.94 TYMP (0.36) DNMT1DHFRGPR84WDR5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2351 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025007415-A1 AZA[3.2.1] BRIDGED RING SUBSTITUTED FLUORESCENT DYE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京大学 2025-01-09 WO claimed
CN-111212647-B Dihydro oxadiazinones 拜耳股份有限公司 2024-05-14 CN claimed
CN-117881670-A Methods of making EGFR inhibitors 缆图药品公司 2024-04-12 CN claimed
CN-117580840-A Synthesis of bis-mesylate salt of 4-amino-N- (1- ((3-chloro-2-fluorophenyl) amino) -6-methylisoquinolin-5-yl) thieno [3,2-D ] pyrimidine-7-carboxamide and intermediates thereof 基因泰克公司 2024-02-20 CN claimed
CN-117510507-A Palladium-catalyzed indoline quinoline derivative synthesized by intramolecular dearomatization of indole and preparation method thereof 河北工业大学 2024-02-06 CN claimed
CN-117343093-A Synthesis method of iron-catalyzed non-activated gem difluoro-bialkylene compound double-silicon-based 山西天宏达安医药科技有限公司 2024-01-05 CN claimed
CN-107690436-B Method for forming complexes, complexes and use thereof 庄信万丰股份有限公司 2023-12-22 CN claimed
CN-116903434-A Copper-catalyzed method for preparing difluoromethyl olefin by hydrodefluorination of trifluoromethyl olefin 凯美克(上海)医药科技有限公司 2023-10-20 CN claimed
CN-116874449-A (R) -4-propyl-dihydrofuran-2-one and purification method and application thereof 四川奥邦古得药业有限公司 2023-10-13 CN claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
US-5962744-A USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-10-05 US claimed
EP-0715615-B1 METHOD FOR PREPARING (+)-(1R)-CIS-3-OXO-2-PENTYL-1-CYCLOPENTANEACETIC ACID FIRMENICH & CIE (CH) 1998-10-07 EP claimed
WO-1998028074-A1 NOVEL SUPPORTED CATALYSTS SETON HALL UNIVERSITY (US) 1998-07-02 WO claimed
EP-0839819-A1 Method of preparing optically active diphosphine ligands Takasago International Corporation (JP) 1998-05-06 EP claimed
EP-0746410-A4 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INST OF TECHN (US) 1997-04-09 EP claimed
EP-0746410-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-12-11 EP claimed
EP-0525070-B1 PHOTOVOLTAIC CELLS ECOLE POLYTECH (CH) 1995-12-20 EP claimed
WO-1995022405-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-08-24 WO claimed
EP-0503884-B1 Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1995-07-26 EP claimed
EP-0631571-A1 PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES. DU PONT (US) 1995-01-04 EP claimed