Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 15/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441739 | 0.90 | ADORA1 (0.61) | TLR8ADORA1ADORA2AADORA2B | |
| SCHEMBL6443635 | 0.84 | ADORA1 (0.57) | TLR8ADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL6443028 | 0.81 | ADORA1 (0.60) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL28748293 | 0.80 | ADORA1 (0.56) | TLR8ADORA1ADORA2AADORA2B | |
| SCHEMBL6443545 | 0.79 | ADORA1 (0.63) | ADORA1ADORA2AADORA2B | |
| SCHEMBL6443531 | 0.77 | ADORA2A (0.55) | TLR8ADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL6442358 | 0.77 | ADORA1 (0.63) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL20434287 | 0.76 | TLR8 (0.66) | TLR8 | |
| SCHEMBL6445232 | 0.74 | ACHE (0.56) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL6440910 | 0.74 | ADORA1 (1.00) | ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |