Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.56 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441108 | 0.91 | ADORA1 (0.61) | ADORA1ADORA2AKDM1ADCUN1D1ADORA2B | |
| SCHEMBL27591986 | 0.80 | TLR8 (0.58) | ADORA1ADORA2ATLR8ADORA2B | |
| SCHEMBL6441820 | 0.76 | ADORA1 (0.57) | ADORA1ADORA2AKDM1ADCUN1D1ADORA2B | |
| SCHEMBL6441869 | 0.74 | ADORA1 (0.65) | ADORA1ADORA2AKDM1ADCUN1D1ADORA2B | |
| SCHEMBL6440878 | 0.73 | ADORA2A (0.63) | ADORA1ADORA2AKDM1ADCUN1D1 | |
| SCHEMBL8889019 | 0.72 | MAPK8 (0.47) | TLR8 | |
| SCHEMBL6443011 | 0.72 | ADORA1 (0.67) | ADORA1ADORA2AKDM1ADCUN1D1ADORA2B | |
| SCHEMBL8889038 | 0.71 | MAPK8 (0.48) | TLR8 | |
| SCHEMBL6440680 | 0.70 | ADORA1 (0.62) | ADORA1ADORA2AKDM1ADCUN1D1ADORA2B | |
| SCHEMBL6441739 | 0.70 | ADORA1 (0.61) | ADORA1ADORA2ATLR8ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |