Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593048 | 1.00 | LMNA (0.40) | LMNAPLGPLATCYP2D6NCF1 | |
| SCHEMBL27611213 | 1.00 | LMNA (0.40) | LMNAPLGPLATCYP2D6NCF1 | |
| SCHEMBL27593233 | 0.86 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL28097052 | 0.86 | CHRM2 (0.30) | LMNAHSD17B10 | |
| SCHEMBL27593232 | 0.86 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL27593040 | 0.86 | NR1H2 (0.37) | LMNAHSD17B10 | |
| SCHEMBL27593039 | 0.86 | NR1H2 (0.37) | LMNAHSD17B10 | |
| SCHEMBL27611217 | 0.84 | PLG (0.41) | LMNAPLGPLATCYP2D6NCF1 | |
| SCHEMBL27729891 | 0.84 | PLG (0.41) | LMNAPLGPLATCYP2D6NCF1 | |
| SCHEMBL27611219 | 0.84 | PLG (0.41) | LMNAPLGPLATCYP2D6NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1582281-A | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-02-16 | — | — | CN | disclosed |