Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593048 | 0.86 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL27593046 | 0.86 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL27593040 | 0.86 | NR1H2 (0.37) | LMNAHSD17B10 | |
| SCHEMBL27593233 | 0.86 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL3603125 | 0.86 | CHRM2 (0.33) | CHRM2CHRM1CHRM3LMNAHSD17B10 | |
| SCHEMBL27611213 | 0.86 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL27593039 | 0.86 | NR1H2 (0.37) | LMNAHSD17B10 | |
| SCHEMBL27593232 | 0.86 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL27613018 | 0.84 | THRA (0.35) | CHRM2CHRM1CHRM3CYP3A4KDM4E | |
| SCHEMBL27594438 | 0.84 | THRA (0.35) | CHRM2CHRM1CHRM3CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-A | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2016-08-31 | — | — | CN | disclosed |